The answer is absolutely yes! Dirt and dust is deposited over boards from the incoming cooling air and is deposited like a blanket over the boards. This dirt and dust can clog air passages under chips blocking vital cooling passages. This makes cooling the servers much more difficult and if this is already a hotspot or trouble area, then it further amplifies the heat load. The Uptime Institute states that for every 10 degree raise in temperature above recommended limits the MTBF (Mean time between failures) will be reduced by 50%.

Managing Data Center Humidity: A Deep Dive Into Sensible and Latent Heat Loads
Understanding sensible vs latent heat helps data center operators manage humidity and cooling performance in controlled environments.
